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You Can't Get There From Here
Jonathan Wells, PhD* - Biology

Volume #4
Spring 2007

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In neo-Darwinism, evolution is explained by the natural selection of small mutational changes in the "genetic programs" that allegedly control embryonic development.

But mutations that produce major changes in development are invariably deleterious, and are thus weeded out by natural selection; so neo-Darwinism assumes that evolution proceeds only (or primarily) through minor changes.

DNA mutations that are beneficial (and thus likely to be naturally selected in the appropriate environments) have been observed, but only at the biochemical level; beneficial mutations in developmental programs have not been observed. In the absence of evidence, the neo-Darwinian view rests entirely on the assumption that genetic programs MUST control development.

This assumption, however, is not supported by the evidence.

To be sure, genes (DNA sequences) affect development, but many lines of research suggest that body plans and other morphological features are laid down prior to and largely independently of gene expression. Genetic mutations affect development primarily by (a) damaging molecules needed for normal development, and (b) damaging binary switches that direct development along pre-determined lines that are not controlled by the genes themselves. 

The first effect is analogous to damaging building materials during the construction of a house; if 2x4s that should be eight feet long are actually shorter or of varied lengths, the shape of the house will be affected.

The second effect is analogous to damaging switches in a railroad switchyard; if cars carrying heating oil destined for Iowa are sent down a siding meant for an Amtrak Metroliner, they will end up in the wrong place.

Features of the fertilized egg that seem to be more fundamental than the genes in controlling development include patterns imprinted on the membrane by the mother, and cytoskeletal patterns generated by centrosomes. In order for evolution to occur, these features (and whatever other features may turn out to be involved) would have to change in concert with the genes.

A neo-Darwinian explanation based on simple changes in DNA sequences is fundamentally incapable of accounting for evolutionarily significant changes in development. Within a neo-Darwinian framework, the organism can't get there from here.

Icons of Evolution - Science or Myth?

*Presented by Jonathan Wells at a Discontinuity seminar, Friday, August 17, 2001, Cedarville University, Cedarville, Ohio. Dr. Wells is a postdoctoral biologist and senior fellow at the Discovery Institute, and hold Ph.D.s from both Yale University and the University of California at Berkeley. His recent book, Icons of Evolution, published by Regnery, has attracted international endorsement.


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Jonathon Wells, PhD

 

 

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